Depression is a type of mental condition that is typically characterized by a continuous sense of sadness and a loss of interest. It affects how patients feel, think, and behave and can cause a variety of mental and physical difficulties. Antidepressants, which are pharmaceuticals that can help decrease symptoms of social anxiety disorder, depression, anxiety disorders, and seasonal affective diso...
Endothelin are the type of therapeutics that inhibits the action of endothelin and is thus effective for treating pulmonary arterial hypertension. This receptor, which plays a major role in regulating vascular tone, is found between the lumen and underlying media of the pulmonary vasculature. For patients suffering from the pulmonary hypertension, the body secrete high amount of endothelin that ca...
NF-κB (Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells) is a transcriptase factor which involves a number of physiological activities cellular process that includes cell proliferation, apoptosis and inflammatory response. Numerous diseases such as tumor, inflammatory joints disorders and asthma involves a NF-κB pathways. NF-κB is the matter of active research among many pharmaceutic...
Rho kinases (ROCKs) inhibitor is a type of rho-associated protein kinase inhibitor a therapeutics belonging to the serine-threonine family. Their function is to target the small GTP-binding protein Rho network that plays an essential role in regulating cell cycle control. ROCK is recommended to be a therapeutic target in several diseases such as ophthalmic diseases, cardiovascular diseases, neurol...
Targeted therapy is to design corresponding therapeutic drugs for the identified cancer-causing site (the site can be a protein molecule inside the tumor cell or a gene fragment) at the cellular molecular level, and the drug enters the body It will specifically select oncogenic sites to combine and act, so that tumor cells will die specifically, without affecting normal tissue cells around the tum...
Amnestic disorder is a group of cognitive defect disorders typically characterized by loss of memories, inability to create new memories and inability to learn new information. It is caused by numerous factors such as ageing, trauma, stroke, stress or lack of sleep and neuronal damage to the parts of brain. It is also a symptom of numerous degenerative brain disorders such as Alzheimer’s disease a...
PD-1/PD-L1 is an important part of the human immune system-a drug target on T cells. Drugs designed for this target can activate the immune effect of T cells on tumor cells, thereby awakening the patient's own anti-cancer effect. tumor effect.
The global market for PD-1 and PD-L1 Drug was estimated to be worth US$ million in 2023 and is forecast to a readjusted size of US$ million by 2030 with a...
Stein-Leventhal syndrome, also known as polycystic ovary syndrome (POCS), is a common health problem among females, usually caused by an imbalance of reproductive hormones. Females having POCS may have excess male hormones (androgens) and have infrequent & prolonged irregular menstrual periods. 27% of females can be affected by the POCS during their childbearing years. Besides irregular ovulation,...
Dermatomyositis is a rare inflammatory skin disorders that is typically characterized by muscle weakness and a severe skin rash. It is mainly caused by either viral infection of the tissues of skeletal muscle or autoimmune reaction. Symptoms may vary broadly from patient to patient. Deformities in the muscles may initiate with weakness and pain in the muscles of the thighs, the hips, the upper arm...
Emetogenic symptoms are associated with nausea and vomiting associated with cancer treatments such as chemotherapy, radiation therapy, and drug therapy. Nausea and vomiting are major side effects of cancer treatment. It is important that nausea and vomiting are controlled so patients can continue treatment and have a better quality of life. Nausea and vomiting, primarily due to, can also be induce...
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