The most widely used line is a subclone (clone 13) of BHK21, usually called as BHK 21(C13), which has been involved in the commercial manufacture of foot and mouth disease vaccines over a twenty year period. BHK-21 cells are susceptible to multiple viruses, including human adenovirus D, reovirus 3, vesicular stomatitis virus and so on.
According to HengCe’s new survey, global Baby Hamster Kidney...
Antibody optimization is the key to the discovery stage of antibody drugs. Optimizing multiple evaluation indicators of antibodies is expected to solve the pain points of existing antibody research and development.
According to HengCe’s new survey, global Antibody Optimization Service market is projected to reach US$ million in 2029, increasing from US$ million in 2022, with the CAGR of % during...
Affinity maturation refers to the rearrangement of antibody genes in lymphatic B cells when the body encounters foreign substances, accompanied by high-frequency mutations in the CDR of the hypervariable region to form lymphatic B cells that can secrete antibodies with different affinities. Subsequently, low-affinity B cells die, and high-specificity and high-affinity B lymphocytes survive and rec...
Monoclonal antibodies are antibodies secreted by a single B lymphocyte clone. Since B lymphocytes can only produce a proprietary antibody against one antigenic determinant, they have highly specific physical and chemical properties, single biological activity, and Antigen binding specificity and other characteristics. After more than 30 years of research and development, monoclonal antibody drugs...
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